Excerpted from GENETIC DISEASES OF THE KIDNEY.

Editors:
Richard Lifton, Yale University School of Medicine, New Haven, CT, USA
Stefan Somlo, Yale University School of Medicine, New Haven, CT, USA
Gerhard Giebisch, Yale University School of Medicine, New Haven, CT, USA
Donald Seldin, Southwestern Medical School, University of Texas, Dallas, USA

ISBN-13: 978-0-12-449851-8
With kind permission of the publisher, Elsevier Inc. For information on the complete textbook, see here.  

chapter 1: genetic approaches to human disease

RICHARD P. LIFTON AND LYNN M. BOYDEN

A basic understanding of the principles of genetics is applied to the understanding human disease.

PDF FIle (pdf, 3.3 MB)

chapter 6: focal segmental glomerulosclerosis

KRISHNA R. POLU AND MARTIN R. POLLAK

The role of genetic factors in the development of focal segmental glomerulosclerosis in humans has become increasingly apparent in recent years. This chapter reviews the recent progress in the understanding of the role of genetic factors in disorders of podocytes related to the development of kidney disease, primarily FSGS.

PDF FIle (pdf, 2.1 MB)