Cochrane Kidney and Transplant

Cochrane Kidney and Transplant

Cochrane is a global independent network of health practitioners, researchers, patient advocates and others, responding to the challenge of making the vast amounts of evidence generated through research useful for informing decisions about health. 

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Cochrane Library: Erythropoiesis-stimulating agents for anemia

Introduction

Introduction

Anemia affects nearly all adults with advanced kidney disease and is linked to fatigue, breathlessness, impaired quality of life and physical function, and shorter survival. ESA treatment aims to improve anemia-related symptoms and minimize treatment-related cardiovascular events. Several ESA classes are available for anemia treatment (epoetin alfa, epoetin beta, darbepoetin alfa, methoxy polyethylene glycol-epoetin beta as well as biosimilar ESAs) but whether these drugs have differing benefits and harms is uncertain. This Cochrane review directly compares available ESAs for treatment of anemia among adults with chronic kidney disease.

Authors

palmer

Suetonia Palmer

Suetonia is a nephrologist based at the University of Otago, Christchurch in New Zealand, and who trained in New Zealand and the USA. She is an Editor for Cochrane Kidney and Transplant.

stipolli

Giovanni Strippoli

Giovanni is a nephrologist based at the University of Bari in Italy, who also trained at the Sydney School of Public Health, Australia. He is an Editor for Cochrane Kidney and Transplant and the journal Nephrology, Dialysis and Transplantation.

 

Copyright© 2015 Cochrane Kidney and Transplant. Published by John Wiley & Sons, Ltd.

 



Saturday, 06 September 2014 13:23


Cochrane Library: Treatment for Lupus Nephritis

Cochrane Library: Treatment for Lupus Nephritis

Introduction

Introduction

Lupus nephritis is an inflammatory condition affecting the kidneys which is caused by systemic lupus erythematosus (SLE), an autoimmune disease that is more common among women. About half of all people with SLE develop lupus nephritis, and of these about 1/10 experience chronic kidney disease or kidney failure. Treatment aims to delay disease progression and achieve remission by stabilising and improving kidney function and minimising side effects. For about the past 30 years, standard treatment for lupus nephritis has focused on a combination of cyclophosphamide (an alkylating agent) and corticosteroids. This Cochrane review assesses the benefits and harms of different immunosuppressive treatments in biopsy-proven proliferative lupus nephritis.

Authors

Henderson

Lorna Henderson

Lorna Henderson is a Nephrologist based in Edinburgh, and who trained in Scotland and Australia. During a fellowship year at Westmead Hospital in New South Wales, Lorna spent some time training with the Cochrane Renal Group, and working on the review update of treatment for Lupus Nephritis. She has an interest in transplantation and evidence based practice.

agnela webster

Angela Webster

Angela is a Nephrologist and Transplant Physician, having trained in England, Scotland and Australia. She also works at the University of Sydney as a Clinical Epidemiologist and is the Deputy Coordinating Editor of the Cochrane Renal Group

 

Copyright© 2014 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

 

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