Thursday, May 22, 2025
2:30 PM CEST
Nephrotic syndrome is among the most frequently encountered kidney conditions in children, yet it poses serious diagnostic and therapeutic dilemmas—particularly when accompanied by impaired kidney function, concurrent infections, or limitations in healthcare infrastructure. In this interactive webinar, pediatric nephrologists from across the globe will analyze a real clinical case that highlights the multifaceted challenges in treating nephrotic syndrome in children.
Attendees will explore key clinical decision points, including when to initiate or adjust immunosuppressive therapy, how to time a renal biopsy in the context of ongoing risk, and practical tactics for preventing and managing infections—a persistent threat in immunocompromised young patients. With a strong emphasis on problem-solving in resource-constrained settings, this session equips clinicians with essential skills to optimize care and outcomes.
Learning Objectives:
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Differentiate between acute and chronic kidney dysfunction in children presenting with nephrotic syndrome and how that distinction influences management.
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Assess risks and benefits of immunosuppression when infection risk is elevated or renal function is compromised.
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Apply evidence-based and context-appropriate strategies to manage pediatric nephrotic syndrome, especially in settings with limited access to diagnostic and therapeutic resources.
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Gain insights into clinical decision-making frameworks that balance efficacy, safety, and resource availability in pediatric care.
Recommended Reading:
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Trautmann A, et al. IPNA clinical practice recommendations for steroid-resistant nephrotic syndrome. Pediatr Nephrol. 2020;35(8):1529-1561.
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Chan EY, Boyer O. Advancements in childhood idiopathic nephrotic syndrome. Pediatr Nephrol. 2024.
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Glenn DA, et al. Risk of infection-related acute care events in glomerular disease. Kidney Med. 2022;4(11).
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O’Grady NP, et al. Intravascular catheter-related infection prevention guidelines. Clin Infect Dis. 2011;52(9).
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Meyrier A, Niaudet P. AKI complicating minimal change disease. Kidney Int. 2018;94(5):861-869.
Moderator:
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Rukshana Shroff (United Kingdom)
Featured Speakers:
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Fanny Tsz-wai Ho (Hong Kong)
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Alison Lap-tak Ma (Hong Kong)
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Gulshan Nigar Chaudhury (Bangladesh)
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Rumana Amin (Bangladesh)
Explore previous Grand Rounds in Pediatric Nephrology content via the ISN Academy
This is a must-attend session for pediatric nephrologists, trainees, and healthcare professionals seeking to refine their clinical approach and improve the quality of nephrology care for children across diverse healthcare landscapes.