Tuesday, May 6, 2025
4:00 PM CEST
Join the International Society of Nephrology (ISN) and the International Society of Endocrinology (ISE) for an exciting interdisciplinary webinar that delves into the dynamic relationships among the gut microbiota, kidney physiology, and endocrine regulation. This event brings together renowned experts to discuss the emerging evidence surrounding the gut-kidney-endocrine axis, a concept that is transforming our understanding of metabolic and renal health.
As scientific understanding evolves, it’s increasingly clear that the gut microbiome serves as more than just a digestive aid — it actively communicates with the endocrine system and the kidneys, influencing inflammation, insulin sensitivity, and even renal filtration. Dysbiosis in the gut has been linked to the onset and progression of conditions such as metabolic syndrome, type 2 diabetes, and chronic kidney disease (CKD).
In this webinar, we will investigate the mechanisms behind this crosstalk, uncover how microbial imbalances contribute to disease progression, and explore how innovative therapies—including GLP-1 receptor agonists, SGLT2 inhibitors, and microbiome-modulating interventions—can be harnessed to support both kidney and metabolic health.
Learning Objectives:
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Elucidate the bidirectional communication between the gut microbiota, renal system, and endocrine pathways.
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Identify how microbial alterations affect the pathogenesis and severity of metabolic and renal disorders.
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Analyze hormonal signaling pathways (e.g., GLP-1, insulin, FGF23) influenced by gut microbes and their systemic impact.
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Evaluate the current and emerging clinical strategies for targeting this axis to slow CKD progression and treat metabolic syndromes.
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Discuss the broader implications of gut-kidney-endocrine synergy in personalized medicine and chronic disease management.
Further Reading:
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Vaziri ND, et al. Kidney Int. 2013;83(2):308–15
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Lau WL, et al. Semin Nephrol. 2021;41(2):104–113
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MacLaughlin HL, et al. AJKD. 2022;79(3):437–449
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Wu IW, et al. Int J Biol Sci. 2020;16(3):420–428
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Cani PD, et al. Curr Pharm Des. 2009;15(13):1546–1558
Moderator:
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Sola Bahous (Lebanon)
Speakers:
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Laetitia Koppe (France)
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Mayur Agrawal (India)
Explore more collaborative content from ISN and ISE on the ISN Academy
Don’t miss this opportunity to enhance your understanding of the gut-kidney-endocrine connection and discover how it is reshaping modern nephrology and endocrinology practice.