Thanks for the answers and thanks the ISN as well for this valuable project. I have read the KDIGO Clinical Practice Guideline for Glomerulonephritis, Volume 2, Issue 2, June 2012. It contains in details what I should do when facing patients with glomerulonephriris.
That’s superb, but my problem is we do not have kidney biopsy here in Cambodia, so what should I do when facing patients with nephritic/nephrotic syndrome?
1. What should I start first? Prednisolone alone or agressively combine with other immuno-suppressive drugs? Some patients come in with severe nephritis pictures with high creatinine, high blood pressure, low hemoglobine,… and I think aggressive treatment would be better and I don’t know what is the cut-off level of those parameters to start combination therapy (please correct me if I am wrong, i.e. I must always start monotherapy first).
2. What should I do next in the management, i.e. how long should I continue prednisolone/other immunosuppressive meds? Doses? Again, thanks for the answers, and detailed ones would be very much appreciated.