Basic Science

Translating Scientific Discovery into Therapeutic Reality for Kidney Disease

Genomic and post-genomic approach and target identification

Approach to genetics of vesicle ureteric reflux

Hemodynamic effects of sun exposure – what is the data, what is the relevance?

Film: The Dog Kidney – Vascular and Tubular Organization of the Kidney

The Case | Azotemia without renal failure

Megalin/cubilin-lysosome-mediated albumin reabsorption is involved in the tubular cell activation of NLRP3 inflammasome and tubulointerstitial inflammation

Mitochondrial quality control and the inflammasome – A sirtuin perspective

APOL1: A rapidly evolving story – Update: Genetics and mechanisms

Will genetics help re-define clinical classification?

Cell tracing to identify fibrogenic cells

The schistosoma mansoni: genetic basis of drug resistance, drug mode of action and drug design

The next generation sequencing revolution

APOL1: Human population genetics

Low nephron number: Compensatory changes in renal function

Film: The Human Kidney; Vascular-Tubular Relationships

INTERACTION BETWEEN POLYCYSTIN-1 AND TSC1/2 AND IT’S ROLE IN REGULATING CANONICAL WNT SIGNALING

Relations vasculo-tubulaires dans le rein des mammifères

Vascular-tubular relationships in the mammalian kidney

The Influence of Renal Vascular Geometry on Oxygen Delivery to Renal Tissue audioicon

Tubulovascular crosstalk in the medullary circulation in hypertension audioicon

Epithelial sodium channels signal in a negative feedback loop in the collecting duct and the mechanism involves NOS1 audioicon

Regulation of Renal Pericyte audioicon

Regulation of prostaglandins by tubule flow audioicon

Role of Cilium in Purinergic Signalling audioicon

Patients, Research and Drugs audioicon

Interaction between academia, industry and government audioicon

What have we learned from animal models of diabetic Nephropathy?

Spleen Tyrosine Kinase (Syk) in Inflammatory Kidney Disease

Fabry Disease: New Treatment Approaches

Qualification of New Translational Kidney Safety Biomarkers for Drug Development

Bioinformatics for understanding diabetic nephropathy audioicon

Approach to Partnership – Academia, Pharma and Governmental Organization: Message from Taiwan audioicon

Integration of experimental approaches and computational models for new therapeutic targets audioicon

Metabolomics in Kidney Disease Research: from metabolomics to new biomarkers and targets audioicon

Histone modifications in kidney disease audioicon

Smad3 for Renal Fibrosis audioicon

Balance of Thymosin Beta4 and AcSDKP – A Novel Target for Fibrosis audioicon

Novel Drugs, Novel Biologics audioicon

Industry-Academic Collaborations: New Ways to Operate audioicon

Immune cells in hypertension: perspectives from experimental data audioicon

Estimated vs Measured GFR for Disease Progression audioicon

Endpoints for AKI studies audioicon

The role of academia in the relation with pharma and regulatory authorities audioicon

A New Initiative: ISN Advisory Committee for Clinical Trials and Studies – ISN ACCTs audioicon

Regulatory Issues and Strategies: U.S. FDA audioicon

PAI-1, Senescence and Aging audioicon

Kidney Health Initiative: Partnership for Innovation and Safety audioicon

Clinical Research of Kidney Disease in China audioicon

Approach to partnership between academia, pharma and governmental organization: message from Latin America audioicon

Respective roles of academia and industry: messages from pharma audioicon

Regulatory Science and Global Clinical Trials audioicon

Dedifferentiation And Transdifferentiation audioicon

First Perspectives Of Kidney Engineering audioicon

Renal Progenitors And Their Implications For Kidney Cancer audioicon

Imaging Glomerular Regeneration audioicon

Cells Of Renin Lineage And Glomerular Injury audioicon

Aqp2-Expressing Progenitor Cells In The Kidney audioicon

Genetic disorders of renal phosphate transport audioicon

Regulation of PHT- dependent signaling and bone homeostasis by beta arresting audioicon

Computational reconstruction of electrical activity in the heart audioicon

Podocytes as a target for insulin: Early intervention and risk prevention audioicon

Mitochondrial Adaptations to Obesity and Lipid Overload audioicon

Signaling Modulators that Support Progression in Diabetic Nephropathy audioicon

Brave New World: Do We Really Want to Know All This? Ethical and Social Impacts of Genomic Research in Nephrology audioicon

Genetic Testing in Chronic Renal Disease, Challenges and Opportunities audioicon

Recapitulating Genetic Variance in the Mouse: First Lessons Learned audioicon

Introduction to Web Based Systems Biology Tools audioicon

Facilitating Renal Disease Researchers in Constructing and Sharing Team Knowledge Across Disciplines and Geographies audioicon

Bridging the Gap in Renal Translational Research: Bringing Large Scale Data Sets into Renal Research Labs audioicon

CDK Network Definition in Syskid audioicon

Systems Approach Identifies HIPK2 as a Critical Regulator of Kidney Tubulointerstitial Fibrosis audioicon

The NHLBI Exome Sequencing Project: Emerging Opportunities for Nephrology audioicon

Additive and Non-additive Genomic Summaries for Outcome Prediction in Chronic Kidney Disease audioicon

Transcriptional Network Analysis of Renal Disease audioicon

Integrative Biology: Lessons to be Learned from Prostate Cancer audioicon

Corin: a key protein of an adaptive renal mechanism to respond to salt variation?