ISN Forefronts Shenzhen 2015 – Presentation Collection

ISN Education features a selection of presentations from the ISN Forefronts Symposium 2015 taking place in Shenzhen, China, on October 22-25, 2015  


These presentations were recorded live from the plenary sessions and therefore include audio and questions. The conference theme this year was ‘Immunomodulation of Cardio-Renal Function’.


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ISN Forefronts Shenzhen 2015 presentations organised by session:

Opening Plenary Session:

Evolutionary medicine: the hypertension pandemic – by Bernard Rossier, Switzerland


SESSION 1: Transcriptomics, Genomics and Epigenetics: 

Epigenetics and diabetic kidney disease – By Alexander Maxwell, UK

Manage my digital life – By Jun Wang

SESSION 2: Innate and Adaptive Immunity, and Renal Pathophysiology

Innate lymphoid cells – New players in tissue injury and repair? – By Jan-Eric Turner

Interaction of the Innate and Cognate Immune System in Nephritis and Renal Transplantation – By Stephen Alexander

The Diverse Function of Macrophages in Renal Disease – By Jeremy Hughes

Angiotensin-converting enzyme 2/MAS receptor double deficiency promotes angiotensin II-induced renal fibrosis by enhancing the ERK1/2 map kinase-SMAD3 crosstalk pathway – By Jun Ni


SESSION 3: Immunology and Metabolism – Immuno-Metabolism, an Emerging Frontier

Modulating mTOR activity to control T cell function – By Hans Stauss

Increased serum platelet microparticle contributes to glomerular endothelial injury in diabetic nephropathy – By Kun Ling Ma


SESSION 5: Immunogenetics, Autoimmunity, and Inflammasome

ANCA-associated vasculitis and immunity – By Ming-hui Zhao

Megalin/cubilin-lysosome-mediated albumin reabsorption is involved in the tubular cell activation of NLRP3 inflammasome and tubulointerstitial inflammation – By Dan Lui


SESSION 6: Hypertension, Metabolism and Immunity

(Pro)Renin Receptor and Blood Pressure Regulation – By Tianxin Yang

The reduction of fumarase activity contributes to elevation of blood pressure in Dahl salt-sensitive rats – By Hou Entai

Neuroimmune communication in hypertension and obesity: A new therapeutic angle? – By YanFei Qi

Autonomic regulation of the immune system and its implications for hypertension – By Matthew Bailey


SESSION 7: Novel Mechanisms in Salt and Water Homeostasis

Th17 cell regulation: The link to salt-sensing and SGK1 Th17 cell phenotype induction – By Chuan We

Dual activation of the bile acid nuclear receptor FXR and G-protein-coupled receptor TGR5 attenuates lithium-induced NDI – By Weidong Wang

Maintaining Balance under Pressure: The role of proximal tubule sodium transport in regulation of extracellular fluid volume and blood pressure – By Alicia McDonough


SESSION 8: Immunity, Atherogenesis and Vascular Function

Macrophage activation and atherogenesis – By Andrew Newby

GSK 3? inhibition promotes macrophage polarization and reduces inflammation and acute and chronic damage following AKI – By Rujun Gong


SESSION 9: Immunity, Fibrosis and Kidney Disease

Immune Cells in Renal Fibrosis: a Role for Dendritic Cells? – By Richard Kitching

Deleting numb from proximal tubules attenuates interstitial fibrosis by mitigating G2/M arrest – By Jing Nie

The molecular basis of circadian clock regulation of collagen homeostasis: implications for fibrosis – By Karl Kadler


SESSION 10: Key Signaling Pathways in Renal and Cardiovascular Disease

TGF-beta/Smad signaling pathway in hypertensive kidney and cardiovascular diseases – By Hui Yao Lan

Podocyte-specific knockout of SIRT6 promotes renal injury by upregulation of NOTCH1 in diabetic nephropathy – By Fan Yi



CLICK HERE to view all presentations from past ISN Forefronts events.

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Last modified on Monday, 30 November 2015 22:34

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