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Friday, 25 December 2015 20:41

Proteinuria as a surrogate marker for renal outcome: are we there yet? (Commentary)

By  Avasare and Radhakrishnan
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Observational studies in glomerular diseases suggest that proteinuria reduction translates to improved outcomes. Because of a dearth of high-quality studies supporting this association, proteinuria is not universally recognized as a surrogate end point. Barbour et al. report on the longitudinal measure of proteinuria that best predicts hard renal outcomes. Their finding that time-varying proteinuria is the most reliable proteinuria metric is a necessary step in establishing proteinuria as a surrogate end point.

 Authors: Rupali S Avasare and Jai Radhakrishnan

Reference: Kidney Int 88: 1228-1230; doi:10.1038/ki.2015.301

Additional Info

  • Language: English
  • Contains Audio: No
  • Content Type: Articles
  • Source: KI
  • Year: 2015
  • Members Only: No
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