Case #13: H13-5186 Renal infarction post-kidney transplantation with fungal infection.
Introduction
Introduction
28 years old male patient received a living unrelated renal transplantation, a month prior to nephrectomy (done for non function).
Discussion
Discussion Case 13
Question #1: The photomicrograph shows in the background, necrosis of the different elements present of the renal tissue ( glomeruli, tubules and interstitium), with extensive infiltration by polymorphonuclear cells. Also noted is a number of branching non-septated fungal hyphae. Patients with kidney transplantation are immunocompromised and the poor irrigation of the allograft as in this case leads to an opportunistic infection represented by the fungal organisms noted in the photomicrograph.
Question #2: The GMS stain is known as one of the two stains of choice for fungal organisms, the other is the PASD stain. The septae of the hyphae react with the silver component of the GMS stain to give the characteristic black color noted in the photomicrograph.