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Friday, 25 December 2015 20:45

The Case | Azotemia without renal failure

By  Hesemann and Morrison
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A 75-year-old male was transferred to our facility from an outside hospital for the management of complications of acute pancreatitis. There he was diagnosed with a common bile duct stone and underwent endoscopic retrograde cholangiopancreatography 6 weeks before transfer. His course was complicated by acute pancreatitis with a pseudocyst compressing the right ureter requiring ureteral stenting and by Clostridium difficile infection. All nutrition and hydration was given by tube feeds via a gastrojejunostomy tube, including 3 g/kg/day of protein in an attempt to reverse his 14 kg weight loss. At the time of transfer, laboratory abnormalities included blood urea nitrogen (BUN) concentration of 96 mg/dl, creatinine (Cr) of 0.88 mg/dl, albumin 2.8 g/dl, alkaline phosphatase of 238 U/l, and lipase 197 U/l. Other electrolytes were normal. At the time of admission to the outside hospital his BUN was 16 mg/dl, and Cr was 0.8 mg/dl. Three days before transfer his BUN was 77 mg/dl. The patient reported that his urine output was significantly reduced such that he was voiding very small amounts once or twice per day. Computed tomography at our facility showed pneumobilia and gas in the right renal collecting system (Figure 1), not seen on imaging 2 weeks prior. When asked directly, the patient admitted to pneumaturia.

 Authors: Laura E Hesemann and Aubrey R Morrison

Reference: Kidney Int 88: 1459-1460; doi:10.1038/ki.2015.127

Additional Info

  • Language: English
  • Contains Audio: No
  • Content Type: Articles
  • Source: KI
  • Year: 2015
  • Members Only: No
Read 246 times Last modified on Wednesday, 06 January 2016 13:03

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