Cochrane Library: Treatment for Lupus Nephritis Featured

Cochrane Library: Treatment for Lupus Nephritis



Lupus nephritis is an inflammatory condition affecting the kidneys which is caused by systemic lupus erythematosus (SLE), an autoimmune disease that is more common among women. About half of all people with SLE develop lupus nephritis, and of these about 1/10 experience chronic kidney disease or kidney failure. Treatment aims to delay disease progression and achieve remission by stabilising and improving kidney function and minimising side effects. For about the past 30 years, standard treatment for lupus nephritis has focused on a combination of cyclophosphamide (an alkylating agent) and corticosteroids. This Cochrane review assesses the benefits and harms of different immunosuppressive treatments in biopsy-proven proliferative lupus nephritis.



Lorna Henderson

Lorna Henderson is a Nephrologist based in Edinburgh, and who trained in Scotland and Australia. During a fellowship year at Westmead Hospital in New South Wales, Lorna spent some time training with the Cochrane Renal Group, and working on the review update of treatment for Lupus Nephritis. She has an interest in transplantation and evidence based practice.

agnela webster

Angela Webster

Angela is a Nephrologist and Transplant Physician, having trained in England, Scotland and Australia. She also works at the University of Sydney as a Clinical Epidemiologist and is the Deputy Coordinating Editor of the Cochrane Renal Group


Copyright© 2014 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.


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Last modified on Thursday, 13 August 2015 12:44

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