Follow Us:

social twitter box white 32 social facebook box blue 32social linkedin box blue 32ISN Blog

Wednesday, 03 April 2013 11:36

Renal Pathology Case 2

Rate this item
(10 votes)

67 years old female patient, presented with SOB for 2 months, found to have anemia with renal impairment and nephrotic range proteinuria.

Click an image:


Test your Knowledge:


Additional Info

  • Language: English
  • Contains Audio: No
  • Content Type: Case/Images
  • Source: ISN
  • Year: 2013
  • Members Only: No
Read 7636 times Last modified on Friday, 28 March 2014 11:16
Hala Kfoury

Hala Kfoury Kassouf is Associate Professor of Pathology at the King Saud University Hospital in Saudi Arabia.

Leave your comments

Post comment as a guest

Your comments are subjected to administrator's moderation.
terms and condition.
Load Previous Comments
  • Guest - Mahmoud

    A little easy because on Immunofluorescence picture 2 is written lambda: in this studying marro is mandatory

    Dr Mahmoud

  • Guest - Rosa Ramos

    Guest - Mahmoud

    Yes, I agree. In this case bone marrow is mandatory

  • Guest - Qayyum

    Good cases. I would recommend a brief explanation at the end of the quiz of all the answers for our junior residents

  • Guest - Prof. Dr. Muhammed Mubarak

    Guest - Qayyum

    I also agree with this suggestion. In fact, the other way round may be more interesting. The juniors should comment on these and finally the case provider should sum up and bring forth important points for the diagnosis. This will generate interest in the junior residents.

  • Guest - Prof Gertruida van Biljon, Pae

    Paediatric nephrologists actually dont see these conditions

  • Guest - Roozbeh

    Dear colleague
    Why you didnt attach the Light microscopy of biopsy as its a first approach to any nephrotic cases.
    Jamshid Roozbeh
    Professor of nephrology,Shiraz Iran

  • Guest - mohammad forghani

    hi dear dr . thanx for case presentation.Good luck and I hope you also to introduce another interesting case....

  • Guest - Suzana Melo

    Please avoid abreviations. It's a international forum.
    Thanks a lot.


    Hi! That is quite good case in term of bright illustration of clinical settings and EM-pattern for LCDD. At the same time IF is not representable and doesn't show light chain restriction. I'd prefer to look at PAS stain for complete explanation of clinical data namely nephrotic range proteinuria. I wonder if there is nodular glomerulopathy or secondary segmental glomerulosclerosis. Presented IF and EM both show only tubular changes.

  • Guest - swetha

    the EM shows tubular electron dense deposits in the subendothelial location. the IF shows linear kappa light chain deposition on tubular epithelium which is negative for lambda, so this a case of monoclonal deposition disease, light chain type...
    nice case

Global Operations Center

Rue des Fabriques 1
1000 Brussels, Belgium
Tel: +32 2 808 04 20
Fax: +32 2 808 4454
Email contact


Americas Operations Center

340 North Avenue 3rd Floor
Cranford, NJ 07016-2496, United States
Tel: +1 567 248 9703
Fax: +1 908 272 7101
Email contact